Season 16 of Supernatural is not confirmed, but it seems Ackles and Padalecki would be down for it. While speaking at the 2024 Creation Honolulu convention, both actors confirmed that there are talks of more Supernatural.

Even years after the show's finale, the pair seem as close as ever, with them working together on Padalecki's Walker and their families spending time together as if the actors are brothers, and not just colleagues playing powerful brothers on Supernatural, one of TV's most successful fantasy series.